In response to an increase in colorectal cancer rates in younger people, the American Cancer Society released a change in its screening guidelines to recommend adults at average risk begin CRC screening starting at age 45 instead of 50. Not all health societies, government models, or payors have responded yet. However, the news does reflect the observation that colon cancer rates are going down for all age groups except the younger patients. This group has been dramatically on the rise. The guidelines were released today and published in CA: A Cancer Journal for Clinicians.