Depression with GI symptoms may mean IBD

It has long been recognized that depression can lead to GI symptoms. But do all GI symptoms in the setting of depression mean only depression? A recent study by Jonathan Blackwell et al at St George’s University of London found that depression, in the absence of prior GI symptoms, is not associated with subsequent development

Thoughts on how IBD emerges in developing countries

It has long been noted that rates of IBD increase as nations develop. What drives this increase in “developing” nations, and what factors keep inflammatory bowel disease (IBD) rates high in the West? Gilaad G. Kaplan, MD, of the Department of Medicine, University of Calgary, discusses the epidemiological stages of IBD and reviews how disease

Dividing Crohn’s Into Small Bowel and Colonic Diseases?

Parambir S. Dulai, MD, and colleagues at the Division of Gastroenterology, University of California San Diego have written a thoughtful discussion on the problem with phenotypes in Crohn’s disease. We have long known that there are different types of disease, aggressiveness factors, and presentations. However, we tend to think of Crohn’s as one disease. Is

Anti-TNF therapy in early pregnancy tied to preeclampsia

“We know that women with inflammatory bowel disease when they are pregnant are at increased risk for adverse pregnancy outcomes,” Sunanda V. Kane, MD, a gastroenterologist and professor of medicine at Mayo Clinic in Rochester, Minnesota, said at the American College of Gastroenterology Annual Meeting. Control of IBD has been felt to be fundamental for

C. dif and IBD patients benefit from FMT

Patients with both Clostridiodes difficile infection and inflammatory bowel disease showed improvement after fecal microbiota transplantation, Jessica Allegretti, MD, director of the FMT program at Brigham and Women’s Hospital, said during a presentation at Digestive Disease Week. The ICON study took place at four sites across the US. Results for FMT in C. dif alone

Anxiety, depression prevalent in IBD patients

Patients with inflammatory bowel disease may also have undiagnosed anxiety and depression, according to a study by Charles Bernstein, MD, of the University of Manitoba in Canada. Researchers evaluated the prevalence of undiagnosed depression and anxiety by analyzing data from a cohort study of psychiatric comorbidity in immune-mediated disorders, including IBD. About a third of