Patients’ Perceptions of PPI Risks

A recent article shows patient safety concerns about PPI’s are common and strongly associated with attempts at discontinuation, with or without a provider’s recommendation. Patients at high risk for GI bleeding, who clearly benefit from PPI’s, were just as likely to have tried stopping PPI’s as others. Physicians should always discuss the risks and benefits

Reflux treatments reduce risk of esophageal cancer

GERD affects 10% to 20% of adults in Western populations and has been known to be an increased risk factor for esophageal adenocarcinoma. Research on the association between antireflux medication or surgery and risk for esophageal adenocarcinoma has remained limited, although the typical approach has been to treat reflux aggressively when there are precancerous changes like

Long-term PPI use no greater risk for Alzheimer’s patients

Several articles have shown an increased risk of fractures with PPI use as patients get older. Sanna Torvinen-Kiiskinen, PhD, of Kuopio Research Centre of Geriatric Care at the University of Eastern Finland, and colleagues wrote that an association between proton pump inhibitor (PPI) use and risk for fractures remains unclear due to contradictory study findings, and

Robotic Surgery in Esophageal Cancer

Robot-assisted surgeries are becoming more commonplace, and having greater success. They have become state of the art for prostatic and pelvic surgeries and have a widespread recognition for being superior in the right hands. A recent randomized trial showed robotic laparoscopic esophagectomy led to significantly fewer complications while achieving similar cancer control, compared with open

Hi-Def Colonoscopy for IBD

A recent study in The American Journal of Gastroenterology found high-definition colonoscopy was as effective as dye spraying chromoendoscopy and virtual chromoendoscopy in the detection of neoplastic lesions in patients with inflammatory bowel disease. We use high-definition endoscopy at The Endoscopy Center of the North Shore, as well as Evanston and Glenbrook Hospitals. Read the

Bacteria linked to esophageal cancer

Patients with higher levels of Tannerella forsythia bacteria, which can be associated with gum disease, may have a greater risk of esophageal cancer. The increase may be as much as 21% according to a study in Cancer Research. Other bacteria, for example Streptococcus and Neisseria bacteria, were linked to decreased risk. “Our study indicates that

42% of cancer cases linked to 17 modifiable risks

New research examined a total of 1,570,975 cancer cases. During the analysis, 26 cancer types and 17 risk factors were analyzed. These 17 risk factors are called “modifiable” because people can take active measures to change them. In the new study, such factors included: alcohol intake smoking (both first- and second-hand) excess body weight a low content of

Recurrence of reflux after surgery

A study found 17.7% of patients who had primary laparoscopic anti-reflux surgery experienced recurrent gastroesophageal reflux disease, researchers reported in the Journal of the American Medical Association. For patients who had recurrent reflux, 16.4% had a second surgery and 83.6% went on long-term anti-reflux medication. Study: 17.7% of patients get GERD after anti-reflux surgery