Fluoroquinolone risks expanded

The FDA recently released results of a review that found an increased risk of aortic ruptures or tears with the use of fluoroquinolones.  As part of the safety warning, the FDA has recommendations for providers, including avoidance of fluoroquinolones in patients with a history of aortic aneurysm or those at risk for an aneurysm; to

Low-gluten diet benefits may be due to low fiber

Healthy adults had less bloating, increased well-being, and a small but significant weight loss on low-gluten compared with high-gluten diets, a study published in Nature Communications found. However, the study found those benefits may be linked to the diet’s dietary fiber rather than lack of gluten. “Gluten-free may not necessarily be the healthy choice many

Weeding out the ‘good’ and ‘bad’ of probiotics for our patients

Dr. Hecht is Professor of Medicine and Microbiology/Immunology and Chief, Gastroenterology and Nutrition at Loyola University Chicago.  She is the former President of the American Gastroenterological Association. In a guest commentary in cooperation between the American Gastroenterological Association and Healio, Dr. Hecht offers advice on how health care professionals can best discuss probiotics with their patients. See the article

Gut Bacteria May Contribute to Multiple Sclerosis

A study recently published in the seminal scientific journal Nature suggests that byproducts of microorganisms living in the gut may influence the progression of neurodegenerative diseases, such as multiple sclerosis (MS). The proposed mechanism is via control of the interaction of microglia and astrocytes. Microglia and astrocytes modulate inflammation and neurodegeneration in the central nervous system (CNS). The findings may

Weight loss after bariatric surgery increases risk of gallstones

Bariatric surgery that brings about rapid weight loss also raises the risk of hospital admissions for pancreatitis, gallstones and other gallbladder conditions by 10 to 100 times, researchers reported at the ACG Annual Scientific Meeting. The researchers said physicians may want to prescribe bile acid sequestrants to patients to reduce the risk of gallstones and

Marital stress and leaky gut?

Yes, that title leads to all kinds of imagery! “Leaky gut syndrome” is a hypothetical condition that is believed to cause chronic inflammation throughout the body and may result in a wide range of conditions. Proposed sequelae include chronic fatigue syndrome, rheumatoid arthritis, lupus, migraines, multiple sclerosis, and autism. The proposed mechanism is that the intestinal

Identifying IBS biomarkers will improve treatment

Identifying biomarkers and symptoms will allow doctors to shorten the length of time it takes to find an effective treatment for IBS patients, writes Dr. William Chey of Michigan Medicine. IBS is not a single disease but likely is several issues that have similar symptoms, Chey writes. Unfortunately, no reliable markers which distinguish the subtypes

IBS may be diagnosed with bowel sounds

Nobel Prize winning gastroenterologist Barry Marshall discusses research in which the diagnosis of IBS may be made with bowel sound analysis. The underlying processes which lead to symptoms of IBS are well studied, well characterized, but not well understood in their entirety. Abnormalities of perception, gut rhythm, stool production, the microbiome, and the neuroendocrine system

Young, obese African-Americans have more severe NAFLD

Obese African-American youths had more severe nonalcoholic fatty liver disease, but overall NAFLD was more common among obese white or Hispanic youth, according to a study in Hepatology. Earlier studies have shown Hispanic adults and children had the highest rates of NAFLD, while African-Americans have a lower likelihood of developing hepatic fat accumulation. See the