Preparation Crucial for Adolescents Transferring to Adult IBD Care
Psychological readiness, logistical barriers, appropriate selection of adult care providers is key. See the article on MedPage here.
Shared inflammatory pathways and genetics may predispose patients with respiratory conditions to developing IBD Ever-mounting evidence is strengthening the link between inflammatory bowel disease (IBD) and immune-mediated respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Research has suggested that IBD and airway illnesses likely share common inflammatory pathways as well as predisposing
Safe conception and pregnancy during treatment, but also at issue: body image, sexuality, cervical cancer risk Inflammatory bowel disease (IBD), affecting approximately one in 500 people in the United States, occurs about equally in men and women. But gender-specific physiologic and psychological differences can have an impact on patient care and outcomes, especially in females
Delay in IBD diagnosis may be linked to stunted growth in children
Canadian researchers found an independent correlation between delay in pediatric inflammatory bowel disease diagnosis and height impairment, with every one standard deviation decrease in height-to-age z-score tied to a nearly 70% higher diagnostic delay risk. The findings in the Archives of Disease in Childhood also showed an independent link between bloody diarrhea and a reduced
The contribution of environmental factors, diet, and related issues like the status of the microbiome once again come into focus in a recent medical article. A Canadian study in The American Journal of Gastroenterology linked living in a rural area with a lower risk of inflammatory bowel disease. The protective effect was particularly strong among
Link Between Antibiotics and IBD Remains Circumstantial Effect stronger in children, and underscores need for antibiotic stewardship in prescribing for pediatric infections Since inflammatory bowel disease (IBD) is linked to disruption of the intestinal microbiome, antibiotics have come under increasing scrutiny as possible environmental catalysts in IBD – especially if taken in early childhood. So
Considerable interest has arisen in recent years regarding the role of the human microbiome in health and disease, including in inflammatory bowel disease (IBD) — a category of disease that includes ulcerative colitis and Crohn’s disease and is thought to result from the interplay between immune system alterations, environmental triggers, genetic factors, and the interaction
About 18.5% of patients with moderate to severe ulcerative colitis experienced remission after taking tofacitinib for eight weeks, compared with 8.2% of patients taking a placebo, researchers reported in The New England Journal of Medicine. In another trial, remission was experienced after one year by 34.3% of patients taking a 5-mg dose of tofacitinib and
Vedolizumab demonstrated significantly greater efficacy as induction and maintenance therapy for UC than placebo in patients naive to TNF antagonists and patients with TNF antagonist failure. There were numerically greater treatment differences at Week 6 among patients receiving vedolizumab who were naive to TNF antagonists than patients with TNF antagonist failure. An AGA Reading Room
Researchers said Crohn’s disease and ulcerative colitis have distinct microbiomes, which could help physicians differentiate between them and reduce the use of diagnostic endoscopy. The study reported in the journal Gut included analysis of 2,045 fecal samples and showed patients with Crohn’s had less microbial diversity and a less stable microbiome compared with UC patients.
