De-Escalation of PPI Therapy

The American Gastroenterological Association has released a new Clinical Practice Update providing best practice advice on how to approach de-prescribing proton pump inhibitors (PPI) in ambulatory patients. See the AGA website information here.

Patients’ Perceptions of PPI Risks

A recent article shows patient safety concerns about PPI’s are common and strongly associated with attempts at discontinuation, with or without a provider’s recommendation. Patients at high risk for GI bleeding, who clearly benefit from PPI’s, were just as likely to have tried stopping PPI’s as others. Physicians should always discuss the risks and benefits

No single test identifies reflux as the etiology for extra-esophageal symptoms.

It is well recognized that reflux can be causal in subgroups of patients with chest and ENT symptoms like asthma, cough, hoarseness, sore throat, sinusitis, and ear pain. However, the possibility of reflux as the cause for a variety of ENT symptoms is both overestimated and often abused. In fact, the cause of extraesophageal symptoms

GERD linked to head and neck cancer risk

According to a study published online Dec. 21 in JAMA Otolaryngology-Head & Neck Surgery, data for 13,805 patients aged 66 and older found that gastroesophageal reflux disease was linked to an increased risk of malignancy of the larynx, oropharynx, hypopharynx, tonsil, nasopharynx and paranasal sinuses. “GERD is associated with the presence of malignancy of the (upper aerodigestive

GERD symptoms tied to psychological factors

  A study in The American Journal of Gastroenterology found that people who did not get heartburn symptom relief from standard treatments but did not have detectable reflux tended to experience more distress and have a poorer quality of life, while symptoms for those with diagnosed gastroesophageal reflux disease who did not respond to proton

Recurrence of reflux after surgery

A study found 17.7% of patients who had primary laparoscopic anti-reflux surgery experienced recurrent gastroesophageal reflux disease, researchers reported in the Journal of the American Medical Association. For patients who had recurrent reflux, 16.4% had a second surgery and 83.6% went on long-term anti-reflux medication. Study: 17.7% of patients get GERD after anti-reflux surgery