Use domperidone with caution

Clinicians should advise patients taking domperidone for gastroparesis to inform their other heath care practitioners and check to ensure there are no interactions with other medications, writes ACG Past President Dr. David Johnson of the Eastern Virginia Medical School. An American College of Gastroenterology guideline states that gastroparesis patients who cannot take metoclopramide can use

Recurrence of reflux after surgery

A study found 17.7% of patients who had primary laparoscopic anti-reflux surgery experienced recurrent gastroesophageal reflux disease, researchers reported in the Journal of the American Medical Association. For patients who had recurrent reflux, 16.4% had a second surgery and 83.6% went on long-term anti-reflux medication. Study: 17.7% of patients get GERD after anti-reflux surgery

“Data on risk of dementia from PPIs conflicts with earlier publications”

An NIH-supported study of 10,486 patients found no link between proton pump inhibitor use and patient risks for mild cognitive impairment, Alzheimer’s disease and dementia, based on patient-reported data of PPI use. The data, reported in the Journal of the American Geriatrics Society, contradict findings of two other recent studies. “The current findings do not