Awareness of nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) is low among Americans who have risks associated with the diseases, according to a survey presented at the NASH Summit in Boston. Many clinical trials are currently underway regarding pharmacologic interventions in an area where diet and lifestyle are failing to curb rising incidence
Obese African-American youths had more severe nonalcoholic fatty liver disease, but overall NAFLD was more common among obese white or Hispanic youth, according to a study in Hepatology. Earlier studies have shown Hispanic adults and children had the highest rates of NAFLD, while African-Americans have a lower likelihood of developing hepatic fat accumulation. See the
Cross-Epidemic of Hepatitis C with Diabetes, Obesity, and Kidney Disease
A cross-sectional and prospective analyses of 13,726 participants in the third National Health and Nutrition Examination Survey found that individuals with chronic hepatitis C have a high burden of major cardiometabolic comorbidities. Diabetes and chronic kidney disease, in particular, are associated with substantial excess mortality in persons with chronic hepatitis C. See the article
A fatty liver index of 30 or greater was tied to a greater risk of colorectal adenoma, and high-index patients had more adenomas and more advanced adenomas than those with a low-index, according to a study in the Diseases of the Colon & Rectum. “The high fatty liver index may be a useful predictor of
A study in JAMA Neurology linked fatty liver disease to an accelerated risk of atrophic brain disease compared to normal aging. Researchers said NAFLD did not appear to be linked to indications of other brain injuries or stroke. The reduced brain volume linked to non-alcoholic fatty liver disease (NAFLD) is equivalent to an extra 4.2
Finnish researchers found that individuals with diabetes or a high waist circumference who consumed higher average amounts of alcohol were at an increased risk of developing liver disease. The findings in the journal Hepatology, based on an analysis of the Finnish Health 2000 study data involving 6,732 individuals without liver disease, revealed that the
NAFLD Linked to Higher Incidence Rates of Cancer Significantly associated with HCC, colon cancer in men, and breast cancer in women Nonalcoholic fatty liver disease (NAFLD) was tied to an increased risk of hepatocellular carcinoma (HCC), colorectal cancer in men, and breast cancer in women, South Korean researchers found. Adjusted results from an observational meta-analysis
