MR Enterography and Small-Bowel Healing in Crohn’s

A Japanese study published in The American Journal of Gastroenterology showed magnetic resonance enterography (MRE) may effectively evaluate small-bowel endoscopic healing in Crohn’s disease and predict patient outcomes similar to balloon-assisted small bowel enteroscopy (BAE). Researchers found patients who did not show small-bowel healing on MRE or BAE had a higher risk of relapse, hospitalization

Neurologic Manifestations in IBD

Neurologic involvement in inflammatory bowel disease (IBD) is uncommon but probably underreported, and gastroenterologists must be ready to recognize it. For example, peripheral neuropathy is reported to occur in up to 13% of IBD patients. Neurologic complications due to nutritional deficiencies are thought to be even more common. Complications may arise spontaneously from the systemic inflammation

Peripheral blood eosinophilia may be biomarker of severe IBD

A longitudinal study in the American Journal of Gastroenterology found that elevated peripheral blood eosinophils found in the white-cell differential of blood tests might better predict the severity of inflammatory bowel disease in a subgroup of patients. “These results are very important, as we are always searching for predictors of more severe disease in order

Airway Disease and IBD

Shared inflammatory pathways and genetics may predispose patients with respiratory conditions to developing IBD Ever-mounting evidence is strengthening the link between inflammatory bowel disease (IBD) and immune-mediated respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Research has suggested that IBD and airway illnesses likely share common inflammatory pathways as well as predisposing

Gender-Specific IBD Burden Heavier for Women

Safe conception and pregnancy during treatment, but also at issue: body image, sexuality, cervical cancer risk Inflammatory bowel disease (IBD), affecting approximately one in 500 people in the United States, occurs about equally in men and women. But gender-specific physiologic and psychological differences can have an impact on patient care and outcomes, especially in females

Delay in IBD diagnosis may be linked to stunted growth in children

Canadian researchers found an independent correlation between delay in pediatric inflammatory bowel disease diagnosis and height impairment, with every one standard deviation decrease in height-to-age z-score tied to a nearly 70% higher diagnostic delay risk. The findings in the Archives of Disease in Childhood also showed an independent link between bloody diarrhea and a reduced

Factors identified which can predict risk in colitis

Clinical measures can predict risks in acute severe colitis A study in the Journal of Gastroenterology and Hepatology found evaluating clinical features in patients with acute severe colitis may help predict the long-term risk of colectomy and steroid dependence. The four measures included in the study were patient response on day seven of hospitalization, steroid

Rural living may reduce IBD

The contribution of environmental factors, diet, and related issues like the status of the microbiome once again come into focus in a recent medical article. A Canadian study in The American Journal of Gastroenterology linked living in a rural area with a lower risk of inflammatory bowel disease. The protective effect was particularly strong among

Antibiotics and IBD

Link Between Antibiotics and IBD Remains Circumstantial Effect stronger in children, and underscores need for antibiotic stewardship in prescribing for pediatric infections Since inflammatory bowel disease (IBD) is linked to disruption of the intestinal microbiome, antibiotics have come under increasing scrutiny as possible environmental catalysts in IBD – especially if taken in early childhood. So