A recent article shows patient safety concerns about PPI’s are common and strongly associated with attempts at discontinuation, with or without a provider’s recommendation. Patients at high risk for GI bleeding, who clearly benefit from PPI’s, were just as likely to have tried stopping PPI’s as others. Physicians should always discuss the risks and benefits
GERD affects 10% to 20% of adults in Western populations and has been known to be an increased risk factor for esophageal adenocarcinoma. Research on the association between antireflux medication or surgery and risk for esophageal adenocarcinoma has remained limited, although the typical approach has been to treat reflux aggressively when there are precancerous changes like
From the AGA website, here is a nice review of the data thus far and how to alleviate your patients’ concerns. See the AGA review here.
A recent study in the Annals of Internal Medicine found people who consumed very hot tea and alcohol every day had a fivefold higher risk of esophageal cancer, compared with those who drank tea less than once per week and consumed less than 15 grams of alcohol daily. People who drank very hot tea daily
