“CLENPIQ” Colonoscopy Instructions

Preparation for colonoscopy involves a restricted diet, drinking the prep with the goal of clearing the colon, fasting prior to the procedure, and some further instructions regarding blood thinners and having a ride. Please review this page and download the detailed Special Instructions below and make sure to follow all of these steps.

These are the general instructions for this prep. The provider may give you alternate instructions during your consultation. Make sure that you confirm the location where you are having your procedure (directions for the possible locations are listed below). Keep in mind that you need to arrive 30 minutes prior to your scheduled appointment time. You will also need to schedule a Covid-19 test prior to your procedure, unless you have been fully vaccinated.


Endoscopy Center of the North Shore, 1100 Central Ave. Suite H, Wilmette, IL 60091 (847) 256-1855, Fax (866)375-3001 Office Directions

Evanston G.I. Lab, 2650 Ridge Ave. Suite 1134, Evanston, IL 60201 (847) 570-2236 or (847) 570-2298. Registration/ Covid Testing: 888-364-6400 Evanston Hospital Directions

  • 6 Days Before
    • See instructions below on blood thinners. Each one has a different duration. Talk to your PCP or cardiologist.
    • No elective NSAID’s
    • No iron
    • Send your registration papers back to office
    • Arrange a ride
    • Pick up Clenpiq, one bottle of magnesium citrate (OTC), and a small box of simethicone (OTC)
    • Arrange COVID testing (Unless fully vaccinated, if so, please send a copy of your vaccination card)
  • 3 Days Before
    • Make sure you have picked up the preparation medications at the pharmacy
    • Magnesium citrate is OTC. Don’t forget to buy this.
    • Limit fiber, seeds, and nuts
  • The Day Before
    • Light breakfast without fiber
    • Clear liquids only rest of the day – Avoid red or Purple
    • Discontinue metformin-containing diabetes medications
  • 7PM The Day Before
    • Drink the Clenpiq followed by 5 glasses of clear liquids
    • Take 250 mg of simethicone at bedtime
    • Nothing by mouth after midnight except prep
  • The Day Of:(Between midnight and 4hrs prior to procedure)
    • Drink the 2nd dose of Clenpiq followed by 5 glasses of clear liquids
    • Take the magnesium citrate if stools are not clear
    • You MUST finish all prep 4 hours before your procedure so plan ahead
    • Arrive to the G.I. Lab 30 minutes early (as directed)

 7PM the day before.

 Must be finished four hours before test.

A note about anesthesia:

If you have special anesthesia needs, we encourage you to make an office appointment. All procedures done at the office involve the use of propofol and an anesthesiologist. For the hospital, this has to be arranged. You will not be able to drive home because of the use of anesthesia or sedation.

A note about billing:

You may see charges for consultation or physical exam as well as the procedure. You may see separate bills from the hospital, anesthesiologist, and pathologist.


Dr. Mehta will speak to you before you leave. Dr. Mehta will generally give you a copy of your actual procedure note.

Special Instructions:

  • If you are on a blood thinner talk to your physician whether it can be discontinued and when. Do not discontinue unless OK’d by primary doctor, cardiologist, or other prescribing doctor.
    • Do NOT take elective pain medication such as naproxen or ibuprofen for 6 days before your procedure. Aspirin for your heart is OK.
    • Diabetics should NOT take diabetes medicines the day of the procedure, but you should bring these medicines with you. If you take metformin or a metformin-containing diabetes medication, do NOT take it for 24 hours prior to the procedure. If you have brittle diabetes, talk to your primary doctor or endocrinologist regarding glucose management the day before and the day of the test.
    • You should take all your other regular medications every day, including the day of the procedure.
    • Patients with pacemakers or automatic implantable cardiac defibrillators (AICD) must contact the GI lab once the procedure is scheduled. The hospital may require interrogation of your device before and after the test. The office will NOT perform procedures with AICD’s.
    • Should you cancel your procedure for any reason we ask that you notify the office at least 48 hours in advance or a fee will be charged. 

If you have any questions, call the office well in advance. If you have any urgent issues the night before, you can page the physician through the office number. You can also check the website for FAQ’s.                       

Prep & FAQ’s