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Fluoroquinolone risks expanded

The FDA recently released results of a review that found an increased risk of aortic ruptures or tears with the use of fluoroquinolones.  As part of the safety warning, the FDA has recommendations for providers, including avoidance of fluoroquinolones in patients with a history of aortic aneurysm or those at risk for an aneurysm; to

Rural clinic-pharmacist partnerships improve HCV outcomes

A study published in the Journal of Primary Care & Community Health showed that patients with hepatitis C virus treated at health facilities that served American Indian/Alaska Natives had better outcomes when the clinics collaborated with pharmacists. The study demonstrated that interdisciplinary teamwork improved outcomes in this at-risk and disadvantaged group. This could serve as

Up to 6 mos PPI therapy may not affect bone health

Research recently published in the seminal journal Gastroenterology failed to find evidence of alterations in key markers of bone formation and metabolism in postmenopausal women on PPI’s. The study examined calcium absorption, serum or urine mineral levels, parathyroid hormone, Vitamin D status, or bone-mineral density with 6 months of PPI therapy.   The prospective double-blind study

IBD patients may see relief of inflammation with antidepressants

Inflammatory bowel disease patients who take antidepressants may also get relief from their inflammation, according to a study published in Inflammatory Bowel Diseases. “Apart from improving mood, it is observed that the anti-inflammatory properties of antidepressants may influence the inflammatory response directly,” the authors wrote. “Other research suggests a bidirectional relationship between IBD activity and

Low-gluten diet benefits may be due to low fiber

Healthy adults had less bloating, increased well-being, and a small but significant weight loss on low-gluten compared with high-gluten diets, a study published in Nature Communications found. However, the study found those benefits may be linked to the diet’s dietary fiber rather than lack of gluten. “Gluten-free may not necessarily be the healthy choice many

Most patients over 65 don’t want life expectancy discussions

An online survey conducted in 2016 of a nationally representative group of 878 adults ages 65 and older found 59.4% did not want to talk about their life expectancy. Presented with a hypothetical situation that they were not immediately dying but had a shortened life expectancy, 59.9% indicated life expectancy discussions should not be initiated

Do you spend > 1 hr per day on the toilet?

William Chey, MD, FACG, of the University of Michigan Health System, conducted the survey of 800 patients and 200 gastroenterologists. Shire Pharmaceuticals sponsored the survey. One of the main highlights of the survey, according to Chey, was that more than half of the patients reported that they spent more than an hour a day on